Discover the most popular cities in North America to depart from for unforgettable African adventures, with convenient travel options from major cities across the United States and Canada. Travelers can begin their journey from New York, Los Angeles, Chicago, Atlanta, Washington, D.C., Toronto, Montreal, Vancouver, Calgary, and other major travel hubs, connecting to some of Africa’s most spectacular safari destinations. From these most popular North American cities, you can explore Tanzania’s world-famous Serengeti National Park, iconic Ngorongoro Crater, and breathtaking Tarangire National Park; Kenya’s legendary Maasai Mara and scenic Amboseli National Park; Uganda’s breathtaking Bwindi Impenetrable National Park and remarkable Kibale Forest National Park; and Rwanda’s spectacular Volcanoes and Nyungwe National Parks. Depending on your itinerary, experience the Great Migration, Big Five wildlife, spectacular big cats, mountain gorilla trekking, chimpanzee trekking, incredible birdwatching, breathtaking landscapes, and authentic African cultural experiences.